Tissue-Engineering the Intestine: The Trials before the Trials

Clevers, Hans, Conder, Ryan K., Li, Vivian S.W., Lutolf, Matthias P., Vallier, Ludovic, Chan, Sarah, Grikscheit, Tracy C., Jensen, Kim B. & De Coppi, Paolo

Published: 06/06/2019

Building complex tissues requires the development of innovative interdisciplinary engineering solutions. In this Forum, the INTENS Consortium discuss experimental considerations and challenges for generating a tissue-engineered intestine for the treatment of short bowel syndrome, taking into account cell source, scaffold choice, and design strategy for achieving proper assembly and function.

Full Access Link: Cell Stem Cell