Surgical feasibility of a one-stage cell-based arthroscopic procedure for meniscus regeneration: A cadaveric study

Michella H. Hagmeijer, Lucienne A. Vonk, Jan-Willem Kouwenhoven, Roel J.H. Custers, Ronald L. Bleys, Aaron J. Krych, and Daniel B.F. Saris

Published: 01/12/2018


Meniscus injury remains the most common indication for orthopedic surgery, but loss of functioning meniscus tissue is strongly correlated with development of early osteoarthritis. However, current clinical options for tissue engineering of the meniscus are limited. This study demonstrates the feasibility of combining human meniscus cells with mesenchymal stromal cells to enhance a meniscus scaffold for meniscus regeneration in a one-stage solution for partial meniscal deficiency.

Full Access Link: Tissue Engineering - Part C: Methods