Conference Paper

Iron oxide nanoparticles with supramolecular ureidopyrimidinone coating

Chiara Turrina , Patricia Y. W. Dankers , Sonja Berensmeier and Sebastian Schwaminger

Published: 1 August 2022


Superparamagnetic iron oxide nanoparticles are a promising material in nanomedicine, especially for generating magnetically controlled drug delivery systems. We developed an innovative ureidopyrimidinone (UPy) coating based on supramolecular hydrogen bonding units. The synthesized nanoparticles possess a positively charged surface with a hydrodynamic diameter of 177 nm at pH 7 and magnetization of 31 emu g-1. The system has the potential to be modified by drugs or bioactive molecules altered with UPy units.

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